What Fatigue Can Mean
Fatigue can arise from a wide range of causes.
Common and often reversible factors include:
-
Poor sleep or disrupted sleep patterns
-
Stress or burnout
-
Low mood or anxiety
Other causes that may need medical assessment include:
-
Anaemia or nutritional deficiencies
-
Thyroid or hormonal problems
-
Chronic infections or inflammatory conditions
Fatigue is often multifactorial, and understanding the full context is important.


When to Take Fatigue Seriously
You should seek medical advice if you have:
-
Fatigue that is persistent or worsening
-
Associated weight loss or loss of appetite
-
Night sweats or recurrent fevers
-
New or unexplained symptoms alongside tiredness
If fatigue is affecting your daily functioning or not improving, it should be assessed.

Why see a general physycian?
Fatigue rarely has a single, obvious cause.
A general physician looks at sleep, physical health, mental wellbeing, and underlying medical conditions together to build a clear picture.
This is particularly helpful when symptoms are ongoing or difficult to explain.
How We Assess Fatigue
A structured assessment typically includes:
-
A detailed discussion of your symptoms, lifestyle, and sleep
-
Review of your medical history
-
Physical examination
-
Targeted blood tests or investigations where appropriate
This approach helps identify contributing factors without unnecessary testing.

Related Symptoms
-
Breathlessness (shortness of breath)

This information is general and not a substitute for medical advice.
Possible Investigations
(if appropriate)
​Fatigue can have a wide range of causes, including medical, metabolic, and lifestyle factors. Investigations are selected to identify common and treatable contributors based on your symptoms and clinical assessment
Blood tests
May include:
-
Full blood count (to assess for anaemia)
-
Iron studies
-
Vitamin B12 and folate
-
Thyroid function
-
Blood glucose and metabolic profile
-
Inflammatory markers
IMAGING
​
Imaging is not routinely required but may be arranged if suggested by your symptoms or examination findings.
OTHER ASSESSMENTS
Depending on your symptoms:
-
Review of sleep patterns and contributing factors
-
Blood pressure measurement
-
Assessment of medications and lifestyle factors
-
Further referral where appropriate
Investigations focus on identifying reversible or treatable causes of fatigue, while avoiding unnecessary or low-yield testing.
